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This paper presents a porcine long bone model, where the goal is to simulate the healing of porcine long bones in a time-dependent manner to improve the process of designing orthopedic devices and implants. A software named BoneDynamics is developed to numerically simulate the bone regeneration process. The model and material properties are first reviewed, and then the model is reconstructed to compare the result of simulated and actual bone regeneration processes. The simulated bone regeneration process is then classified into three stages. The bone regeneration stages are compared with the actual bone regeneration process, and then the best simulation method of the proposed bone regeneration stages is found. Finally, a process of the healing of long bone defect in time series simulations is compared with the healing in two stages, the fracture healing and the intramembranous and endochondral bone formation stages. The simulation result shows that the simulation of the intramembranous bone and endochondral bone healing processes matches the real data. Therefore, the long bone healing process is simulated by using the fracture healing process, and the bone regeneration process is simulated as the integration of the fracture healing process and the intramembranous and endochondral bone formation stages.
The flow curves of aluminum alloy die-casting at different degrees of addition and different mold temperatures are obtained by simulation. Corresponding curves of the processing parameter and the results of experiment are similar. The reasons are that the experimental conditions and the rules of simulation are the same, the influence on the results of simulation by the mold temperature is small, and the accuracy of simulation is good.
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